Critical mission computing as communication real-time infrastructure for systems for integrated control of complex industrial systems. Architecture of high performance control system and its integration with decision support and business information systems. Design of critical software components optimized for real-time operation under heavy load. Design of simulation test-beds for verification of complex software systems and evaluation of their real-time performances. Reliability and availability of distributed control system. Redundant structures. Security and safety aspects. Industrial communications and networks applied in critical infrastructure systems. Case studies of different real-world critical mission systems.