This course comprises mechanical models, the language of equations and information technologies for the purpose of getting insight into questions on normal and pathological states of human body as well as the processes determining the boundary between this two. Despite the quantitative nature of their arguments because they use numbers and intervals of acceptable values to make decisions on diagnosis and treatments, most of clinical physicians, during their training and practice, use only verbal descriptions of the sequences leading from normal to pathological states considering both cell and system physiology. In the last decades in journals, monographs and textbooks on medicine, a large number of results appeared as a result of research that crosses the barriers between scientific disciplines. Hemodynamics, nephrology, neurology and pulmonology are now related to models and carefully designed measurements. Thus course is based on selected chapters of the below references.