Modeling and simulation of biophysical processes at the molecular, sub–cellular and cellular levels. Specific biophysical processes that will be studied are the following: interactions between ions and cytoskeleton protein structures (microtubules and actin filaments), ionic conductivity of cytoskeletal structures and ionic currents in cells, electron transfer in DNA, electron flow through proteins, diffusion and transport across cell membrane and membrane potential, excitation and propagation of nerve signals, action potential in neurons, transport of biological macromolecules inside and through cell membrane, dynamics of cytoskeletal motor proteins and signaling mechanisms within the cell, electrodynamic interactions between cancer and healthy cells, cancer growth, drug diffusion and targeted drug delivery strategies. Using commercially available software packages for numerical simulations (Matlab or another high–level programming language). Part of the course takes place through individual study and research work in the field of modeling and simulation of biophysical processes. The study and research work is based on active study of primary scientific sources, establishing new or improving present biophysical models, numerical simulations and performing a number of in silico experiments, as well as writing a paper in the narrow scientific field within the topic of the doctoral dissertation.